8.0 Excellent
New York, United States

The Chemists Club Hotel

★★★★ — New York, United States
8.0 Excellent
Overview

The Chemists Club Hotel

Look, I'll be honest – when I first walked into The Chemists Club Hotel, I wasn't expecting much from what looked like just another Midtown building on 41st Street.

Look, I’ll be honest – when I first walked into The Chemists Club Hotel, I wasn’t expecting much from what looked like just another Midtown building on 41st Street. But this place actually surprised me in the best way possible. It’s housed in what used to be an actual chemists’ club (hence the name), and they’ve kept all these gorgeous original details that make you feel like you’re stepping into some sort of elegant speakeasy from the 1920s. The lobby has these dark wood panels and vintage scientific instruments scattered around – not in a cheesy theme park way, but more like someone’s brilliant grandfather was a mad scientist with impeccable taste.

What really won me over about this four-star spot is how it manages to feel both historic and completely modern at the same time. The rooms are honestly better than I expected – they’ve got this rich, sophisticated vibe with deep colors and brass fixtures, but everything actually works perfectly. The beds are ridiculously comfortable (I’m talking sink-right-in good), and the bathrooms have these amazing rain showers that I may have stayed in a bit too long. You know what’s nice? The windows are thick enough that you can barely hear the street noise, which in New York is basically a miracle. I stayed on the seventh floor and could actually sleep past 7 AM without garbage trucks waking me up.

The location is sort of perfect if you ask me – you’re right in Murray Hill, so you can walk to Grand Central in about five minutes, but you’re not dealing with the absolute chaos of Times Square tourists. There’s a really solid coffee shop called Birch literally around the corner, and if you head down to 40th Street, you’ll find some great little restaurants that aren’t completely overpriced tourist traps. The hotel staff actually knows the neighborhood too, which sounds basic but you’d be surprised how many places just hand you a generic map. They pointed me toward this amazing ramen spot on 39th that I never would have found otherwise. I mean, parking is still New York parking (expensive and annoying), but the front desk folks were helpful about directing me to the least terrible garage nearby. It’s one of those places where the service feels genuine rather than scripted – they remember your name after day one and actually seem to care whether you’re having a good time.

Accommodations

Our Rooms

Classic King Room

Max. people: 2
1 king bed
From $457 / night
Select Room →

Deluxe King Room

Max. people: 2
1 king bed
From $477 / night
Select Room →

Deluxe Queen Room

Max. people: 2
1 queen bed
From $481 / night
Select Room →

Double Room - Mobility/Hearing Accessible with Roll-In Shower

Max. people: 2
2 full beds
From $518 / night
Select Room →

Junior Suite

Max. people: 2
1 king bed
From $692 / night
Select Room →
Guest Voices

Guest Reviews

8.0
Excellent Based on 10 reviews
Staff
9.4
Comfort
9.5
Location
9.7
Free Wifi
9.3
Facilities
9.0
Cleanliness
9.4
Value for money
8.6
Filter:
S
Sandie Guernsey September 9, 2025
9

Would recommend as position and rooms are great.

Location fantastic. Room larger than usual in NYC. Staff very helpful especially Lance.
Allowed early check in as room was ready.
Steamer rather than iron.

What could be improved: There were 4 of us but only 2 bottles of water each day. Snacks not topped up.
Sockets not near mirror for drying hair.
Little unpacking space.

L
Laura United Kingdom September 8, 2025
10

Had a great stay at the chemists club and the staff were very friendly and welcoming.

Location was perfect,

What could be improved: N/A

E
Elaine Switzerland September 7, 2025
10

Perfect location, cozy and clean.

The location was perfect, close to the UN and to main attractions. The staff were all kind and helpful. The room was comfortable and clean.

R
Roslyn United States September 4, 2025
10

Wonderful stay - and I plan to return

Our room was clean, modern, quiet. That’s difficult to say in Manhattan when you’re on a busy street.

What could be improved: Lots of construction around, but you can can’t control that. It’s all over the city.

N
Natasha United States September 3, 2025
10

Lovely accommodation for a visit to NYC

Well located to Grand Central, Bryant Park and the theater district. Extremely comfortable and elegant room. Loved having water and snacks included

L
Linda United States August 30, 2025
9

Quiet, clean, so close to Grand Central.

Very close to Grand Central, quiet, very clean rooms, wonderful friendly staff.

What could be improved: Nothing enjoyed our stay.

O
Osama Saudi Arabia August 30, 2025
10

Exceptional

Excellent experience and staff

K
Kathleen United States August 27, 2025
10

Chemist Club is the place to stay in NYC.

Nicely appointed. Hotel is worthy of return trips. Nadiyah @ the front is knowledgeable and proficient @ her job. Such high praises deserved for a gracious woman. Shout out to Benjamin’s Steak house adjacent to the hotel is 5 stars plus!

What could be improved: Water pressure on 3rd floor (#302) was lacking.

T
Tatyana United States August 27, 2025
9

Elegant and charming with sumptuous beds

Very friendly staff, comfy beds, clean space and beautiful rooms. Great location :)

A
Anastassiya United States August 27, 2025
10

Exceptional

Amazing customer service and very comfortable room!

Find Us

Location

52 East 41st Street, Murray Hill, New York, NY 10017, United States

Surroundings

What's nearby:

  • Bryant Park550 m
  • Grace Plaza700 m
  • Verizon Plaza600 m
  • Channel Gardens950 m
  • Chrysler Building350 m
  • Rockefeller Center1 km
  • Empire State Building900 m
  • Tudor Grove Playground750 m
  • Mary OConnor Playground750 m
  • Morgan Library & Museum400 m

Restaurants & cafes:

  • Restaurant Stout0 m
  • Restaurant Dill & Parsley10 m
  • Restaurant Homefront Deli100 m

Top attractions:

  • Central Park4 km
  • Herald Square1.1 km
  • Top of the Rock1.1 km
  • Flatiron Building1.6 km
  • Strawberry Fields3.2 km
  • The Highline Park3.1 km
  • Museum of Modern Art1.3 km
  • One World Trade Center6 km
  • Metropolitan Museum of Art3.8 km
  • National September 11 Memorial & Museum5 km

Natural Beauty:

  • Peak Kings Bluff (31m)5 km
  • Lake Conservatory Water2.9 km

Public transit:

  • Train Grand Central Station150 m
  • Train New York Penn Station1.7 km
  • Subway Grand Central - 42nd Street200 m
  • Subway Fifth Avenue €“ Bryant Park400 m

Closest Airports:

  • La Guardia Airport12 km
  • Teterboro Airport17 km
  • New York Skyports Seaplane Base2.5 km
Reserve Your Stay

The Chemists Club Hotel

New York, United States

Get in Touch

Send Us a Message

Fill out the form below, and one of our concierge specialists will get back to you promptly.





    Looking for the perfect place to stay?
    I'll help you find the best stay in New York!